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IMMUNOGLOBULIN GAMMA-CHAINS
Descriptors Found:
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DeCS
Descriptor
English
:
Immunoglobulin gamma-Chains
Descriptor
Spanish
:
Cadenas gamma de Inmunoglobulina
Descriptor
Portuguese
:
Cadeias gama de Imunoglobulina
Synonyms
English
:
Immunoglobulins, gamma-Chain
Tree Number:
D12.776.124.486.485.114.619.393.522
D12.776.124.486.485.705.500.380
D12.776.124.790.651.114.619.393.522
D12.776.124.790.651.705.500.380
D12.776.377.715.548.114.619.393.522
D12.776.377.715.548.705.500.380
Definition
English
:
Heavy chains of
IMMUNOGLOBULIN G
having a
molecular weight
of approximately 51 kDa. They contain about 450 amino acid residues arranged in four domains and an oligosaccharide component covalently bound to the Fc fragment constant region. The gamma heavy chain subclasses (for example, gamma 1, gamma 2a, and gamma 2b) of the
IMMUNOGLOBULIN G
isotype subclasses (IgG1, IgG2A, and IgG2B) resemble each other more closely than the heavy chains of the other
IMMUNOGLOBULIN ISOTYPES.
Indexing Annotation
English
:
gammopathy: coordinate
IMMUNOGLOBULIN GAMMA-CHAINS
(IM) with
PARAPROTEINEMIAS
(IM) but consider also
HYPERGAMMAGLOBULINEMIA
(IM) or
HEAVY CHAIN DISEASE
(IM), follow text; DF: IG GAMMA CHAIN
Pharmacological Action:
Immunologic Factors
History Note
English
:
2006 (1976)
Allowable Qualifiers
English
:
administration & dosage
adverse effects
analysis
biosynthesis
blood
cerebrospinal fluid
chemistry
classification
contraindications
drug effects
diagnostic use
economics
genetics
history
immunology
isolation & purification
metabolism
pharmacology
physiology
poisoning
radiation effects
toxicity
therapeutic use
ultrastructure
urine
Record Number:
30361
Unique Identifier:
D007142
Occurrence in VHL
:
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